---
title: SeqOne somaHRD
description: SeqOne somaHRD, a versatile, cost efficient and clinically validated HRD solution
---

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### somaHRD, a versatile, cost efficient and clinically validated HRD solution

**SeqOne’s somaHRD** offers:

- Machine learning clinically validated solution against reference PAOLA-1 cohort
- Seamless lab workflow integration with sWGS & BRCA Panel results into a single report and Agilent Magnis single flowcell (panel + sWGS)
- Compatibility with all wetlabs
- Transparent reporting, including QC metrics, actionable information

[Clinical evaluation of a low-coverage whole-genome test for detecting homologous recombination deficiency in ovarian cancer, European Journal of Cancer, 2024](https://doi.org/10.1016/j.ejca.2024.113978)

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## Transparent reporting, actionable information

[![Screenshot 2024-03-04 at 21.36.05](https://hubspot.seqone.com/hs-fs/hubfs/Screenshot%202024-03-04%20at%2021.36.05.png?width=888&height=1318&name=Screenshot%202024-03-04%20at%2021.36.05.png)](https://hubspot.seqone.com/hubfs/Screenshot%202024-03-04%20at%2021.36.05.png?hsLang=en)

- One line HRD status summary
- % cellularity (provided by the pathologist)
- Confidence interval of the HRD probability
- Low tumor profile status detected by sWGS analysis
- HRD probability score features: 
    - LGA (Large genomic Alteration Status)
    - LPC (Loss of Parental Copy Status)
- BRCA/TP53  pathogenic SNV/indels and VAF details
- Copy number variation at CCNE1 provided and profiles per chromosome

## SeqOne Genomic analysis platform

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### Secure. Scalable. Proven.

- Used in Routine by 1000+ users in multiple very high-volume labs
- Free trial testing, transparent usage-based pricing (‘fee per analysis’)
- Unlimited user accounts and secured cloud health data storage at no additional costs.
- International Customer Support and Application Specialists.
- Automated data workflow from Sequencer (upload, analysis, exports) with SeqOne Data Sync
- Compliant with data privacy and requirements with ISO/IEC 27001:2013 certifications and guaranteed data residency

 

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