---
title: What's new in SeqOne in October 2025?
description: Read SeqOne’s 1.48 release note to discover the new features in October 2025, including major enhancements to the Reporting tools, GnomAD filtering, a COSMIC upgrade, and the release of SomaMethyl!
---

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1. [Test\_SeqOne](https://hubspot.seqone.com/test_seqone?hsLang=en)
2. [Releases](https://hubspot.seqone.com/test_seqone/releases?hsLang=en)
3. [Release Notes 2025](https://hubspot.seqone.com/test_seqone/releases?hsLang=en#release-notes-2025)

# What's new in SeqOne in October 2025?

## Read SeqOne’s release note to discover the new features in October 2025

Welcome to the October 2025 release (v1.48) of the SeqOne Platform! 

This update is packed with features designed to give you more flexibility and power in your daily work. Create stunning, professional reports with our revamped **reporting module**, dive into methylation analysis with the brand-new **SomaMethyl pipeline**, and accelerate your somatic interpretations with **DiagAI Autofill**. We've also enhanced our **germline** workflows with the support of PacBio variant data, and more robust variant detection to make your analyses even more powerful. 

[Read on for all the details](https://139813491.hs-sites-eu1.com/release-note-v1.48-en?hsLang=en)!

 

- [Releases](https://hubspot.seqone.com/test_seqone/releases?hsLang=en#main-content)

    - [Spring 2026](https://hubspot.seqone.com/test_seqone/releases?hsLang=en#spring-2026)
    - [Release Notes 2025](https://hubspot.seqone.com/test_seqone/releases?hsLang=en#release-notes-2025)
    - [What's new in Preview?](https://hubspot.seqone.com/test_seqone/releases?hsLang=en#whats-new-in-preview)
- [Analysis & Interpretation](https://hubspot.seqone.com/test_seqone/analysis-interpretation?hsLang=en#main-content)

    - [Variant table](https://hubspot.seqone.com/test_seqone/analysis-interpretation?hsLang=en#variant-table)
    - [Workflow Management](https://hubspot.seqone.com/test_seqone/analysis-interpretation?hsLang=en#workflow-management)
    - [Annotation and Scores](https://hubspot.seqone.com/test_seqone/analysis-interpretation?hsLang=en#annotation-and-scores)
    - [Reporting](https://hubspot.seqone.com/test_seqone/analysis-interpretation?hsLang=en#reporting)
    - [DiagAI](https://hubspot.seqone.com/test_seqone/analysis-interpretation?hsLang=en#diagai)
    - [Coverage and Metrics](https://hubspot.seqone.com/test_seqone/analysis-interpretation?hsLang=en#coverage-and-metrics)
    - [CNV](https://hubspot.seqone.com/test_seqone/analysis-interpretation?hsLang=en#cnv)
- [Getting started](https://hubspot.seqone.com/test_seqone/getting-started?hsLang=en#main-content)

    - [General Platform Usage](https://hubspot.seqone.com/test_seqone/getting-started?hsLang=en#general-platform-usage)
    - [Intro to worksets](https://hubspot.seqone.com/test_seqone/getting-started?hsLang=en#intro-to-worksets)
    - [Video Tutorials](https://hubspot.seqone.com/test_seqone/getting-started?hsLang=en#video-tutorials)
    - [Files](https://hubspot.seqone.com/test_seqone/getting-started?hsLang=en#files)
    - [Intro to Platform Features](https://hubspot.seqone.com/test_seqone/getting-started?hsLang=en#intro-to-platform-features)
- [Troubleshooting](https://hubspot.seqone.com/test_seqone/troubleshooting?hsLang=en#main-content)

    - [General](https://hubspot.seqone.com/test_seqone/troubleshooting?hsLang=en#general)
    - [Credentials](https://hubspot.seqone.com/test_seqone/troubleshooting?hsLang=en#credentials)
    - [Error and info messages](https://hubspot.seqone.com/test_seqone/troubleshooting?hsLang=en#error-and-info-messages)
- [Information Security & Compliance](https://hubspot.seqone.com/test_seqone/information-security-compliance?hsLang=en#main-content)

    - [General](https://hubspot.seqone.com/test_seqone/information-security-compliance?hsLang=en#general)
- [AI Systems Documentation](https://hubspot.seqone.com/test_seqone/ai-systems-documentation?hsLang=en#main-content)

    - [DiagAI Autofill](https://hubspot.seqone.com/test_seqone/ai-systems-documentation?hsLang=en#diagai-autofill)
    - [DiagAI HPO](https://hubspot.seqone.com/test_seqone/ai-systems-documentation?hsLang=en#diagai-hpo)
- [Technical Information](https://hubspot.seqone.com/test_seqone/technical-information?hsLang=en#main-content)

    - [Workflows - Somatic](https://hubspot.seqone.com/test_seqone/technical-information?hsLang=en#workflows-somatic)
    - [Technical details](https://hubspot.seqone.com/test_seqone/technical-information?hsLang=en#technical-details)
    - [Databases](https://hubspot.seqone.com/test_seqone/technical-information?hsLang=en#databases)

# SeqOne

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